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Overdose of Nutriflex Peri/Nutriflex Plus is not to be expected on proper administration.
Symptoms of fluid and electrolyte overdose: Hyperhydration, polyuria, electrolyte imbalance and pulmonary oedema.
Symptoms of amino acid overdose: Renal amino acid losses with consecutive amino acid imbalances, sickness, vomiting, shivering, headache, metabolic acidosis, and hyperammonaemia.
Symptoms of glucose overdose: Hyperglycaemia, glucosuria, dehydration, hyperosmolality, hyperglycaemic-hyperosmolar coma.
Treatment: Immediate cessation of infusion is indicated for overdose.
Further therapeutic measures depend on the particular symptoms and their severity. Disorders of the carbohydrate and electrolyte metabolism are treated by insulin administration and appropriate electrolyte substitution, respectively. When infusion is recommenced after the symptoms have declined it is recommended that the infusion rate be raised gradually with monitoring at frequent intervals.
